Physical Biology of the Materials–Microorganism Interface

The chemistry/biology interface.

Novel bioactive compounds derived from microorganisms and plants are frequently used for the treatment of diseases as well as powerful tools to understand basic physiological phenomena. In recent decades, chemical biology has extended this research and attracted much attention serving as a bridge between chemistry and biology. Enormous technological developments and innovative ideas have contri...

The Physical Foundation of Biology

Physical Biology of the Cell

ble to the interested lay reader, but perhaps not specific enough for those already familiar with genetics as a biological and cultural entity. As all the chapters argue against various forms of genetic determinism, many make the same general points — that while DNA is certainly critical, its role has been exaggerated and misinterpreted and it should really be understood as one of many particip...

Systems interface biology.

The field of systems biology has attracted the attention of biologists, engineers, mathematicians, physicists, chemists and others in an endeavour to create systems-level understanding of complex biological networks. In particular, systems engineering methods are finding unique opportunities in characterizing the rich behaviour exhibited by biological systems. In the same manner, these new clas...

Cell biology at the host–microbe interface

Manipulation of membrane dynamics Nihal Altan-Bonnet (National Institutes of Health) described positive-sense RNA enteroviruses that manipulate the host to generate phosphatidylinositol 4-phosphate (PI4P) and cholesterol-rich membrane platforms for efficient viral replication. The enzyme PI4KIIIβ is hijacked by the enteroviral protein 3A to generate new pools of PI4P at these membrane platforms...